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Cynthia S. Cook, DVM, PhD
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This dense corneal opacity is caused by calcium deposition within corneal stroma. It is most often associated with non-specific senile degeneration or, less commonly, with chronic inflammation. It may also reflect systemic abnormalities, namely hypothyroidism and hypercholesterolemia. As in this case, there is often a secondary keratitis, similar to a foreign body reaction, in response to the deposit. Discomfort is variable and usually associated with corneal ulceration. In severe cases, removal of the deposit by superficial keratectomy is indicated. Healing of the cornea following keratectomy may be slow and recurrence of the deposits is possible. Thus, surgery is reserved for those cases where ulceration is chronic and/or recurrent.
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